Crigler-Najjar’s syndrome

Interesting medical story that reminds me of an episode of House:

John Crigler remembers being baffled by the jaundice disease he encountered among Amish newborns when he was a young pediatrician working with Najjar at Johns Hopkins Hospital in Baltimore. The babies all died.

“There wasn’t any treatment, any hope, any cure,” said Crigler, now 87. “We were just spectators. There was nothing we could do.”

Patients began living longer in the 1970s when doctors realized that the wavelength and energy of blue light changes the nature of the bilirubin, allowing it to be excreted from the body.