Evidence for the inflammation hypothesis of Alzheimer’s

The inflammation hypothesis of Alzheimer’s, which suggests that inflammation in the brain triggers a cascade of cellular events that over time results in deposits and atrophy, and subsequent cognitive deficits, is still relatively controversial.

A Harvard researcher found a correlation between inflammation and future prevalence of Alzheimer’s.

The participants’ blood was tested for levels of cytokines, which are protein messengers that trigger inflammation. Those with the highest amount of cytokines in their blood were more than twice as likely to develop Alzheimer’s disease as those with the lowest amount of cytokines.